Nebenwirkungen · Hycamtin
HYCAMTIN 0.25 mg hard capsules HYCAMTIN 1 mg hard capsules · Abschnitt 4.8 · PDF-Seite 21
HOS-086099 · Präparat HOS-083256
Thrombocytopenia Severe thrombocytopenia (Grade 4 - platelets <10 x 109/l) occurred in 6% of patients in 2% of courses. Median time to onset of severe thrombocytopenia was day 15 with a median duration of 2.5 days. In 18% of courses with severe thrombocytopenia the duration was >7 days. Moderate thrombocytopenia (Grade 3 - platelets between 10.0 and 50.0 x 109/l) occurred in 29% of patients in 14% of courses. Platelet transfusions were given to 10% of patients in 4% of courses. Reports of significant sequelae associated with thrombocytopenia including fatalities due to tumour bleeds have been infrequent.
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Version 2026-01-20T15:26:00Z · SHA-256 b5faba0cb8dc430e883615daec0cf15a62742b0008cf3a57c33ebf39c2a0a4b9 · Passage 2484e73283245738e3542270e37c7aaee4eaecd3913b7f42bf4cff1bc68698c9 · Zeichen 3606–4217 im Abschnitt