Nebenwirkungen · MabThera
MabThera 1600 mg solution for subcutaneous injection · Abschnitt 4.8 · PDF-Seite 93
HOS-087766 · Präparat HOS-083527
IgG levels In the clinical trial evaluating MabThera maintenance treatment in relapsed/refractory follicular lymphoma, median IgG levels were below the lower limit of normal (LLN) (< 7 g/L) after induction treatment in both the observation and the MabThera groups. In the observation group, the median IgG level subsequently increased to above the LLN, but remained constant in the MabThera group. The proportion of patients with IgG levels below the LLN was about 60% in the MabThera group throughout the 2-year treatment period, while it decreased in the observation group (36% after 2 years).
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