Ein Paarvergleich findet Originalpassagen, die den anderen Wirkstoff wörtlich nennen. Aussagen gelten für das jeweilige Präparat und seine Formulierung. Klassenbegriffe und abweichende Synonyme können fehlen. Kein Treffer bedeutet nicht, dass keine Wechselwirkung besteht.
RxNorm 05-Oct-2026 · geprüft 2026-10-25 · 1009 Präparate · 54812 Quellenpassagen · 148 strukturierte Aussagen. Automatisch aktualisiert, ohne menschliche Freigabe.
Wechselwirkungen · Comtess
Comtess 200 mg film-coated tablets · Abschnitt 4.5 · PDF-Seite 4–5
HOS-087880 · Präparat HOS-083575
4
and selegiline were observed in repeated-dose studies in parkinsonian patients. However, the
experience of the clinical use of entacapone with several medicinal products, including MAO-A
inhibitors, tricyclic antidepressants, noradrenaline reuptake inhibitors such as desipramine,
maprotiline and venlafaxine, and medicinal products that are metabolised by COMT (e.g. catechol-
structured compounds: rimiterole, isoprenaline, adrenaline, noradrenaline, dopamine, dobutamine,
alpha-methyldopa, apomorphine, and paroxetine) is still limited. Caution should be exercised when
these medicinal products are used concomitantly with entacapone (see also sections 4.3 and 4.4).
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): maprotiline (HOS-086572) paroxetine (HOS-086246) desipramine (HOS-086249) dopamine (HOS-085948) venlafaxine (HOS-086573) dobutamine (HOS-086565) apomorphine (HOS-086566) selegiline (HOS-086575) methyldopa (HOS-086564)
Vollständigen Kontext in der EMA-Fachinformation lesen →Quellennachweis
Version 2024-09-18T01:00:00Z · SHA-256 fa3d8879d7f9d8835c303451aba5afa0417c9a42bba423f3f71a40c3f8d94d33 · Passage 3c592197fa296402268e76a507959b26c502f61c3b5567c38fa7d68d94e5d6c3 · Zeichen 418–1090 im Abschnitt
Wechselwirkungen · Comtan
Comtan 200 mg film-coated tablets · Abschnitt 4.5 · PDF-Seite 4–5
HOS-087903 · Präparat HOS-083583
4
imipramine or between entacapone and moclobemide. Similarly, no interactions between entacapone
and selegiline were observed in repeated-dose studies in parkinsonian patients. However, the
experience of the clinical use of entacapone with several medicinal products, including MAO-A
inhibitors, tricyclic antidepressants, noradrenaline reuptake inhibitors such as desipramine,
maprotiline and venlafaxine, and medicinal products that are metabolised by COMT (e.g. catechol-
structured compounds: rimiterol, isoprenaline, adrenaline, noradrenaline, dopamine, dobutamine,
alpha-methyldopa, apomorphine, and paroxetine) is still limited. Caution should be exercised when
these medicinal products are used concomitantly with entacapone (see also sections 4.3 and 4.4).
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): maprotiline (HOS-086572) paroxetine (HOS-086246) desipramine (HOS-086249) dopamine (HOS-085948) imipramine (HOS-085907) moclobemide (HOS-087879) venlafaxine (HOS-086573) rimiterol (HOS-087904) dobutamine (HOS-086565) apomorphine (HOS-086566) selegiline (HOS-086575) methyldopa (HOS-086564)
Vollständigen Kontext in der EMA-Fachinformation lesen →Quellennachweis
Version 2026-05-07T16:36:00Z · SHA-256 5a934525674e083ec4dd9056db2e81d6f6bd7e081e45463e4be2195fdd4c2470 · Passage 607c7c228205279947c9a575e4730f7853ea1c18929afcfc4a48e376ed14e9a1 · Zeichen 322–1089 im Abschnitt
Wechselwirkungen · Entacapone Teva
Entacapone Teva 200 mg film-coated tablets · Abschnitt 4.5 · PDF-Seite 4
HOS-213534 · Präparat HOS-155128
In single-dose studies in healthy volunteers, no interactions were observed between entacapone and
imipramine or between entacapone and moclobemide. Similarly, no interactions between entacapone
and selegiline were observed in repeated-dose studies in parkinsonian patients. However, the
experience of the clinical use of entacapone with several medicinal products, including MAO-A
inhibitors, tricyclic antidepressants, noradrenaline reuptake inhibitors such as desipramine, maprotiline
and venlafaxine, and medicinal products that are metabolised by COMT (e.g. catechol-structured
compounds: rimiterole, isoprenaline, adrenaline, noradrenaline, dopamine, dobutamine, alpha-
methyldopa, apomorphine, and paroxetine) is still limited. Caution should be exercised when these
medicinal products are used concomitantly with entacapone (see also sections 4.3 and 4.4).
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): maprotiline (HOS-086572) paroxetine (HOS-086246) desipramine (HOS-086249) dopamine (HOS-085948) imipramine (HOS-085907) moclobemide (HOS-087879) venlafaxine (HOS-086573) dobutamine (HOS-086565) apomorphine (HOS-086566) selegiline (HOS-086575) methyldopa (HOS-086564)
Vollständigen Kontext in der EMA-Fachinformation lesen →Quellennachweis
Version 2021-09-28T17:49:00Z · SHA-256 a1bd223632cc773f7d6b9c4c6c3717b6bb040156eb55488dc0e81428b647ce20 · Passage d28934dc54dbd13dea735cd13a3c66783dab1bfafac92610aa00a62b311d4345 · Zeichen 171–1035 im Abschnitt
Wechselwirkungen · Entacapone Orion
Entacapone Orion 200 mg film-coated tablets · Abschnitt 4.5 · PDF-Seite 4–5
HOS-215641 · Präparat HOS-155488
4
experience of the clinical use of entacapone with several medicinal products, including MAO-A
inhibitors, tricyclic antidepressants, noradrenaline reuptake inhibitors such as desipramine,
maprotiline and venlafaxine, and medicinal products that are metabolised by COMT (e.g. catechol-
structured compounds: rimiterole, isoprenaline, adrenaline, noradrenaline, dopamine, dobutamine,
alpha-methyldopa, apomorphine, and paroxetine) is still limited. Caution should be exercised when
these medicinal products are used concomitantly with entacapone (see also sections 4.3 and 4.4).
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): maprotiline (HOS-086572) paroxetine (HOS-086246) desipramine (HOS-086249) dopamine (HOS-085948) venlafaxine (HOS-086573) dobutamine (HOS-086565) apomorphine (HOS-086566) methyldopa (HOS-086564)
Vollständigen Kontext in der EMA-Fachinformation lesen →Quellennachweis
Version 2024-09-24T11:10:00Z · SHA-256 3eb4e83d0bea670f09b10f71bef77c228824c1e10efb8c36a0cf3aa5315b81fe · Passage dd1d6a1b67875866d02a2feca2ca369e0b23c9161352e02aadb463f889fe1ab8 · Zeichen 511–1090 im Abschnitt
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