Wirkstoffe & Arzneimittelsicherheit

Nebenwirkungen · Targretin

Targretin 75 mg soft capsules · Abschnitt 4.8 · PDF-Seite 8

HOS-091544 · Präparat HOS-084349

Vomiting Diarrhoea1,3 Nausea3 Anorexia1 Pancreatitis1,3 Gastrointestinal Liver Function Tests Abnormal Hepatic Failure disorders Cheilitis2 Gastrointestinal Disorder1 Dry Mouth2,3 Constipation Flatulence Skin Ulcer Alopecia1 Serous Drainage1 Skin Hypertrophy Herpes Simplex Skin and Exfoliative Dermatitis Skin Nodule Pustular Rash subcutaneous Pruritus Acne Skin Discoloration3 tissue disorders Rash Sweating Hair Disorder1 Dry Skin2,3 Nail Disorder1,3 Skin Disorder Musculoskeletal Bone Pain and connective Arthralgia Myasthaenia1 tissue disorders Myalgia Renal and Albuminuria1,3 urinary Kidney Function Abnormal disorders Neoplasm Allergic Reaction Fever1,2,3 General Pain Infection Cellulitis disorders and Headache Chills1 Infection Parasitic administration Asthaenia Abdominal Pain Mucous Membrane Disorder3 site conditions Hormone Level Altered1 Back Pain1,2,3 Lab Test Abnormal 1: adverse reactions noted with increased frequency when bexarotene was administered at a dose >300mg/m2/day. 2: adverse reactions noted with increased frequency when bexarotene was administered at a dose of 300 mg/m2/day in non-CTCL cancer patients. 3: adverse reactions noted with increased frequency when bexarotene was administered at a dose of >300 mg/m2/day (compared to administration to CTCL patients at 300 mg/m 2/day) in non-CTCL cancer patients.

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