Wechselwirkungen · INOmax
INOmax 800 ppm mol/mol medicinal gas, compressed · Abschnitt 4.5 · PDF-Seite 19
HOS-108541 · Präparat HOS-093033
In the presence of oxygen, nitric oxide is rapidly oxidised to derivatives which are toxic to the bronchial epithelium and alveolo-capillary membrane. Nitrogen dioxide (NO2) is the main substance formed, and may cause airway inflammation and damage. There are also animal data suggesting an increased susceptibility to airway infections upon exposure to low levels of NO2. During treatment with nitric oxide, the NO2 concentration should be < 0.5 ppm in the nitric oxide dose range < 20 ppm. If at any time the NO2 concentration exceeds 1 ppm, the nitric oxide dose should immediately be reduced. See section 4.2 for information on monitoring for NO2.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): nitrogen (HOS-108524) oxygen (HOS-087778)
Vollständigen Kontext in der EMA-Fachinformation lesen →Quellennachweis
Version 2025-05-15T11:01:00Z · SHA-256 4c3ecbe485d3d0d3f3d8a8b72af806e039310534c247a674f80a0286630fc6f8 · Passage cea6a1ab7965bdb37e90efea475c57de8233eb69d623f36cec2e0b4797985971 · Zeichen 1790–2543 im Abschnitt