Nebenwirkungen · Kineret
Kineret 100 mg/0.67 ml solution for injection in pre-filled syringe. · Abschnitt 4.8 · PDF-Seite 11
HOS-108763 · Präparat HOS-093075
In a study with 15 SJIA patients followed for up to 1.5 years, one event of transient neutropenia was reported. In a study with 11 patients with Still’s disease (SJIA and AOSD) randomized to Kineret (6 patients) or Placebo (5 patients) and followed for 16 weeks, no neutropenia was reported. In a non- interventional long-term safety study in 306 paediatric patients with Still’s disease followed for up to more than 9 years, (mean duration of treatment course with Kineret was 17.0 (standard deviation 21.1) months and the median duration was 8.9 months), 5 events of neutropenia including 1 event of febrile neutropenia, were reported.
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