Nebenwirkungen · Humira
Humira 20 mg solution for injection in pre-filled syringe · Abschnitt 4.8 · PDF-Seite 20
HOS-111809 · Präparat HOS-093595
Patients had serum samples tested for autoantibodies at multiple time points in rheumatoid arthritis studies I − V. In these trials, 11.9% of patients treated with Humira and 8.1% of placebo and active control − treated patients that had negative baseline anti-nuclear antibody titres reported positive titres at Week 24. Two patients out of 3,441 treated with Humira in all rheumatoid arthritis and psoriatic arthritis studies developed clinical signs suggestive of new-onset lupus-like syndrome. The patients improved following discontinuation of therapy. No patients developed lupus nephritis or central nervous system symptoms.
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Version 2025-10-08T11:41:00Z · SHA-256 0118f9ea31f7b28ac156bc8449293407c25bc43421a73fa92a30fe90db390eca · Passage e459f42ba96983dc2a311ed34a8b042833f37583d9e90eae20ed511e4b20b272 · Zeichen 21937–22568 im Abschnitt