Wirkstoffe & Arzneimittelsicherheit

Nebenwirkungen · Litak

LITAK 2 mg/ml solution for injection · Abschnitt 4.8 · PDF-Seite 6–7

HOS-112296 · Präparat HOS-093643

6 Infections and infestations Very common: infections * (e.g. pneumonia *, septicaemia *) Neoplasms benign, malignant Common: second malignancies * and unspecified (incl cysts and Rare: tumour lysis syndrome * polyps) Blood and lymphatic system Very common: pancytopenia/myelosuppression *, neutropenia, disorders thrombocytopenia, anemia, lymphopenia Uncommon: haemolytic anaemia * Rare: hypereosinophilia Very rare: amyloidosis Immune system disorders Very common: immunosuppression * Rare: graft-versus-host disease * Metabolism and nutrition Very common: decreased appetite disorders Uncommon: cachexia Nervous system disorders Very common: headache, dizziness Common: insomnia, anxiety Uncommon: somnolence, paraesthesia, lethargy, polyneuropathy, confusion, ataxia Rare: apoplexy, neurological disturbances in speech and swallowing Very rare: depression, epileptic seizure Eye disorders Uncommon: conjunctivitis Very rare: blepharitis Cardiac disorders Common: tachycardia, heart murmur, hypotension, epistaxis, myocardial ischemia * Rare: Cardiac failure, atrial fibrillation, cardiac decompensation Vascular disorders Very common: purpura Common: petechiae, haemorrhages * Uncommon: phlebitis Respiratory, thoracic and Very common: abnormal breath sounds, abnormal chest sounds, mediastinal disorders cough Common: shortness of breath, pulmonary interstitial infiltrates mostly due to infectious aetiology, mucositis Uncommon: pharyngitis Very rare: lung embolism Gastrointestinal disorders Very common: nausea, vomiting, constipation, diarrhoea Common: gastrointestinal pain, flatulence Rare: ileus Hepato-biliary disorders Common: reversible, mostly mild increases in bilirubin and transaminases Rare: hepatic failure Very rare: cholecystitis Skin and subcutaneous tissue Very common: rash, localised exanthema, diaphoresis disorders Common: pruritus, skin pain, erythema, urticaria Rare: Stevens-Johnson syndrome/Lyell syndrome Musculoskeletal and connective Common: myalgia, arthralgia, arthritis, bone pain tissue disorders Renal and urinary disorders Rare: renal failure General disorders and Very common: injection site reactions, fever, fatigue, chills, administration site conditions asthenia Common: oedema, malaise, pain * see descriptive section below.

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