Wechselwirkungen · Pedea
Pedea 5 mg/ml solution for injection · Abschnitt 4.5 · PDF-Seite 4
HOS-112955 · Präparat HOS-093805
The concomitant use of Pedea with the following medicinal products is not recommended: - diuretics: ibuprofen may reduce the effect of diuretics; diuretics can increase the risk of nephrotoxicity of NSAIDs in dehydrated patients. - anticoagulants: ibuprofen may increase the effect of anticoagulants and enhance the risk of bleeding. - corticosteroids: ibuprofen may increase the risk of gastrointestinal bleeding. - nitric oxide: since both medicinal products inhibit platelet function, their combination may in theory increase the risk of bleeding. - other NSAIDs: the concomitant use of more than one NSAID should be avoided because of the increased risk of adverse reactions. - aminoglycosides: since ibuprofen may decrease the clearance of aminoglycosides, their co- administration may increase the risk of nephrotoxicity and ototoxicity (see section 4.4).
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): nitric oxide (HOS-088773)
Vollständigen Kontext in der EMA-Fachinformation lesen →Quellennachweis
Version 2025-05-21T15:00:00Z · SHA-256 cea3929d7128e83aae3f8e5875a60eb779627d5bf1d8264e9198df72d11de74b · Passage 3d8e8657aded44c2ba155c0a4657e76aed79199bf7ab7a1bd1bea9c13c73084d · Zeichen 0–875 im Abschnitt