Wechselwirkungen · Noxafil
Noxafil 300 mg gastro-resistant powder and solvent for oral suspension · Abschnitt 4.5 · PDF-Seite 72
HOS-114401 · Präparat HOS-094063
Vinca alkaloids Most of the vinca alkaloids (e.g. vincristine and vinblastine) are substrates of CYP3A4. Concomitant administration of azole antifungals, including posaconazole, with vincristine has been associated with serious adverse reactions (see section 4.4). Posaconazole may increase the plasma concentrations of vinca alkaloids which may lead to neurotoxicity and other serious adverse reactions. Therefore, reserve azole antifungals, including posaconazole, for patients receiving a vinca alkaloid, including vincristine, who have no alternative antifungal treatment options.
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RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): vinblastine (HOS-086220) vincristine (HOS-086219) lead (HOS-085592)
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Version 2026-03-24T12:21:00Z · SHA-256 bfc2a27f2fb2c982d1e4beb55db11eb1ad163481d32f08c94b54ec38f96ef5b5 · Passage cbe843f29b5c7b107831c3fb6e847b5786796b654343df4c4a410c21ae1b17e9 · Zeichen 6805–7389 im Abschnitt