Wechselwirkungen · Aptivus
Aptivus 250 mg soft capsules · Abschnitt 4.5 · PDF-Seite 16
HOS-114833 · Präparat HOS-094169
Simvastatin The HMG-CoA reductase The concomitant use of Aptivus, Lovastatin inhibitors simvastatin and co-administered with low dose No interaction study lovastatin are highly dependent ritonavir, with simvastatin or performed on CYP3A for metabolism. lovastatin are contra-indicated due to an increased risk of myopathy, including rhabdomyolysis (see section 4.3). HERBAL PRODUCTS St. John’s wort Plasma concentrations of Herbal preparations containing (Hypericum perforatum) tipranavir can be reduced by St. John’s wort must not be No interaction study concomitant use of the herbal combined with Aptivus, co- performed preparation St John’s wort administered with low dose (Hypericum perforatum). This is ritonavir. Co-administration of due to induction of drug Aptivus with ritonavir, with St.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): lovastatin (HOS-086157) simvastatin (HOS-086158) ritonavir (HOS-084521)
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Version 2026-04-23T09:35:00Z · SHA-256 1c396190f98e89933229f2261b0e436bd43dac9c1de8e2dacaa36a755dc06dce · Passage deb7cec834abef3ab011fae542ee7cad7c722cd2ba8c6cd45f8390875aae83c9 · Zeichen 33652–34845 im Abschnitt