Wechselwirkungen · Aptivus
Aptivus 250 mg soft capsules · Abschnitt 4.5 · PDF-Seite 21
HOS-114847 · Präparat HOS-094169
Ritonavir is a potent inhibitor of CYP3A4 and therefore affect drugs metabolised by this enzyme. Triazolam Based on theoretical The concomitant use of Aptivus, No interaction study considerations, tipranavir, co- co-administered with low dose performed administered with low dose ritonavir, with triazolam is ritonavir, is expected to increase contraindicated due to potential triazolam concentrations. serious and/or life threatening events (see section 4.3) Inhibition of CYP 3A4 by tipranavir/r Nucleoside analogue DNA polymerase inhibitors Valaciclovir 500 mg Co-administration of valaciclovir, Valaciclovir and Aptivus with single dose tipranavir and low dose ritonavir low dose ritonavir, may be co- was not associated with clinically administered without dose relevant pharmacokinetic effects. adjustment.
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RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): ritonavir (HOS-084521) triazolam (HOS-086168)
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Version 2026-04-23T09:35:00Z · SHA-256 1c396190f98e89933229f2261b0e436bd43dac9c1de8e2dacaa36a755dc06dce · Passage 3c13933b82e9d5525c7497a8850fd2994f8074388a1acf5b4ea9c30dcbbedae6 · Zeichen 55229–56473 im Abschnitt