Wirkstoffe & Arzneimittelsicherheit

Nebenwirkungen · Sutent

Sutent 12.5 mg hard capsules Sutent 25 mg hard capsules Sutent 37.5 mg hard capsules Sutent 50 mg hard capsules · Abschnitt 4.8 · PDF-Seite 12

HOS-115677 · Präparat HOS-094337

Skin and Skin discolourationt Skin exfoliation Erythema subcutaneous Palmar-plantar Skin reactionv multiforme* tissue disorders erythrodysaesthesia Eczema Stevens-Johnson syndrome Blister syndrome* u Rash Erythema Pyoderma Hair colour changes Alopecia gangrenosum Dry skin Acne Toxic epidermal Pruritus necrolysis* Skin hyperpigmentation Skin lesion Hyperkeratosis Dermatitis Nail disorderw Musculoskeletal Pain in extremity Musculoskeletal pain Osteonecrosis of the Rhabdomyolysis and connective * Arthralgia Muscle spasms jaw * tissue disorders Back pain Myalgia Fistula Myopathy Muscular weakness Renal and urinary Renal failure* Haemorrhage Nephrotic disorders Renal failure acute* urinary tract syndrome Chromaturia Proteinuria General disorders Mucosal Chest pain Impaired healing and administration inflammation Pain site conditions Fatiguex Influenza like illness Oedemay Chills Pyrexia Investigations Weight decreased Blood creatine White blood cell phosphokinase count decreased increased Lipase increased Blood thyroid Platelet count stimulating hormone decreased increased Haemoglobin decreased Amylase increasedz Aspartate aminotransferase increased Alanine aminotransferase increased Blood creatinine increased Blood pressure increased Blood uric acid increased * Including fatal events. The following terms have been combined: a Nasopharyngitis and oral herpes. b Bronchitis, lower respiratory tract infection, pneumonia, and respiratory tract infection. c Abscess, abscess limb, anal abscess, gingival abscess, liver abscess, pancreatic abscess, perineal abscess, perirectal abscess, rectal abscess, subcutaneous abscess, and tooth abscess. d Oesophageal candidiasis and oral candidiasis. e Cellulitis and skin infection. f Sepsis and sepsis shock. g Abdominal abscess, abdominal sepsis, diverticulitis, and osteomyelitis. h Thrombotic microangiopathy, thrombotic thrombocytopenic purpura, and haemolytic uraemic syndrome. i Decreased appetite and anorexia j Dysgeusia, ageusia, and taste disturbance. k Acute coronary syndrome, angina pectoris, angina unstable, coronary artery occlusion, and myocardial ischaemia. l Ejection fraction decreased/abnormal. m Acute myocardial infarction, myocardial infarction, and silent myocardial infarction. n Oropharyngeal and pharyngolaryngeal pain. o Stomatitis and aphtous stomatitis. p Abdominal pain, abdominal pain lower, and abdominal pain upper. q Gastrointestinal perforation and intestinal perforation.

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