Wirkstoffe & Arzneimittelsicherheit

Nebenwirkungen · Champix

CHAMPIX 0.5 mg film-coated tablets CHAMPIX 1 mg film-coated tablets · Abschnitt 4.8 · PDF-Seite 51–52

HOS-115981 · Präparat HOS-094383

51 System Organ Adverse Drug Reactions Class Uncommon Seizure, tremor, lethargy, hypoaesthesia Rare Cerebrovascular accident, hypertonia, dysarthria, coordination abnormal, hypogeusia, circadian rhythm sleep disorder Not known Transient loss of consciousness Eye disorders Uncommon Conjunctivitis, eye pain Rare Scotoma, scleral discolouration, mydriasis, photophobia, myopia, lacrimation increased Ear and labyrinth disorders Uncommon Tinnitus Cardiac disorders Uncommon Myocardial infarction, angina pectoris, tachycardia, palpitations, heart rate increased Rare Atrial fibrillation, electrocardiogram ST segment depression, electrocardiogram T wave amplitude decreased Vascular disorders Uncommon Blood pressure increased, hot flush Respiratory, thoracic and mediastinal disorders Common Dyspnoea, cough Uncommon Upper respiratory tract inflammation, respiratory tract congestion, dysphonia, rhinitis allergic, throat irritation, sinus congestion, upper- airway cough syndrome, rhinorrhoea Rare Laryngeal pain, snoring Gastrointestinal disorders Very common Nausea Common Gastrooesophageal reflux disease, vomiting, constipation, diarrhoea, abdominal distension, abdominal pain, toothache, dyspepsia, flatulence, dry mouth Uncommon Haematochezia, gastritis, change of bowel habit, eructation, aphthous stomatitis, gingival pain Rare Haematemesis, abnormal faeces, tongue coated Skin and subcutaneous tissue disorders Common Rash, pruritus Uncommon Erythema, acne, hyperhidrosis, night sweats Rare Severe cutaneous reactions, including Stevens Johnson Syndrome and Erythema Multiforme, angioedema Musculoskeletal and connective tissue disorders Common Arthralgia, myalgia, back pain Uncommon Muscle spasms, musculoskeletal chest pain Rare Joint stiffness, costochondritis Renal and urinary disorders Uncommon Pollakiuria, nocturia Rare Glycosuria, polyuria Reproductive system and breast disorders Uncommon Menorrhagia Rare Vaginal discharge, sexual dysfunction General disorders and administration site conditions Common Chest pain, fatigue Uncommon Chest discomfort, influenza like illness, pyrexia, asthenia, malaise Rare Feeling cold, cyst Investigations Common Liver function test abnormal

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