Wechselwirkungen · Prezista
PREZISTA 75 mg film-coated tablets PREZISTA 150 mg film-coated tablets PREZISTA 600 mg film-coated tablets · Abschnitt 4.5 · PDF-Seite 66
HOS-116533 · Präparat HOS-094447
If parenteral midazolam is If parenteral midazolam is co-administered with PREZISTA co-administered with PREZISTA co-administered with low dose ritonavir it with low dose ritonavir, it should may cause a large increase in the be done in an intensive care unit concentration of this benzodiazepine. (ICU) or similar setting, which Data from concomitant use of parenteral ensures close clinical monitoring midazolam with other protease inhibitors and appropriate medical suggest a possible 3-4 fold increase in management in case of respiratory midazolam plasma levels. depression and/or prolonged sedation. Dose adjustment for midazolam should be considered, especially if more than a single dose of midazolam is administered.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): protease (HOS-085623) ritonavir (HOS-084521) midazolam (HOS-086167)
Vollständigen Kontext in der EMA-Fachinformation lesen →Quellennachweis
Version 2024-07-26T09:44:00Z · SHA-256 457dafbe8b3b9cee45b9ca7b46919ded598e0d0cd16715525d161e54f80b9117 · Passage 99927cb80663f1bd630af55d25edc7631d68419ed3378ccdc01c1b2eeda28a10 · Zeichen 67563–68979 im Abschnitt