Wechselwirkungen · Mycamine
Mycamine 50 mg powder for concentrate for solution for infusion Mycamine 100 mg powder for concentrate for solution for infusion · Abschnitt 4.5 · PDF-Seite 5
HOS-117345 · Präparat HOS-094585
Drug interaction studies in healthy human subjects were conducted to evaluate the potential for interaction between micafungin and mycophenolate mofetil, ciclosporin, tacrolimus, prednisolone, sirolimus, nifedipine, fluconazole, ritonavir, rifampicin, itraconazole, voriconazole and amphotericin B. In these studies, no evidence of altered pharmacokinetics of micafungin was observed. No micafungin dose adjustments are necessary when these medicines are administered concomitantly. Exposure (AUC) of itraconazole, sirolimus and nifedipine was slightly increased in the presence of micafungin (22%, 21% and 18% respectively).
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): prednisolone (HOS-086337) nifedipine (HOS-086289) amphotericin (HOS-088524) voriconazole (HOS-084524) itraconazole (HOS-084516) fluconazole (HOS-087945) tacrolimus (HOS-085202) sirolimus (HOS-085172) ritonavir (HOS-084521) mycophenolate mofetil (HOS-085154)
Vollständigen Kontext in der EMA-Fachinformation lesen →Quellennachweis
Version 2025-08-04T14:40:00Z · SHA-256 b10a8e41df9b387a8b080f2a96c5684a6a8901efa78aaf4c99c300096afa4cf9 · Passage cbe82a5c8fc5ae28a4114fd1888efec3a0d481da438e2fa59ffb5442277ef92b · Zeichen 105–730 im Abschnitt