Wechselwirkungen · Velmetia
Velmetia 50 mg/850 mg film-coated tablets Velmetia 50 mg/1 000 mg film-coated tablets · Abschnitt 4.5 · PDF-Seite 7
HOS-119411 · Präparat HOS-094939
Effects of sitagliptin on other medicinal products Digoxin: Sitagliptin had a small effect on plasma digoxin concentrations. Following administration of 0.25 mg digoxin concomitantly with 100 mg of sitagliptin daily for 10 days, the plasma AUC of digoxin was increased on average by 11 %, and the plasma Cmax on average by 18 %. No dose adjustment of digoxin is recommended. However, patients at risk of digoxin toxicity should be monitored for this when sitagliptin and digoxin are administered concomitantly.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): digoxin (HOS-086172)
Vollständigen Kontext in der EMA-Fachinformation lesen →Quellennachweis
Version 2025-12-01T18:25:00Z · SHA-256 7183443f4b7960ef66f883676c4dbec19622df3ef1cf38be93a3bba4cc1dce84 · Passage 76758bd0459aea51dc21948e8c10cd5e5a1e43d27902191877afacb92de87be0 · Zeichen 4603–5113 im Abschnitt