Wirkstoffe & Arzneimittelsicherheit

Nebenwirkungen · Adcetris

ADCETRIS 50 mg powder for concentrate for solution for infusion. · Abschnitt 4.8 · PDF-Seite 15–16

HOS-126047 · Präparat HOS-096209

15  System organ class Adverse reactions (monotherapy) Adverse reactions (combination therapy) Not known: Progressive multifocal leukoencephalopathy Blood and lymphatic system disorders Very common: Neutropenia Neutropeniaa, anaemia, febrile neutropenia Common: Anaemia, thrombocytopenia Thrombocytopenia Uncommon: Febrile neutropenia Immune system disorders Uncommon: Anaphylactic reaction Anaphylactic reaction Metabolism and nutrition disorders Very common: Decreased appetite Common: Hyperglycaemia Hyperglycaemia Uncommon: Tumour lysis syndrome Tumour lysis syndrome Psychiatric disorders Very common: Insomnia Nervous system disorders Very common: Peripheral sensory neuropathy, Peripheral sensory neuropathya, peripheral motor neuropathy peripheral motor neuropathya, dizziness Common: Dizziness Uncommon: Demyelinating polyneuropathy Respiratory, thoracic and mediastinal disorders Very common: Cough, dyspnoea Cough, dyspnoea Gastrointestinal disorders Very common: Nausea, diarrhoea, vomiting, Nausea, constipation, vomiting, constipation, abdominal pain diarrhoea, abdominal pain, stomatitis Uncommon: Pancreatitis acute Pancreatitis acute Hepatobiliary disorders Common: Alanine aminotransferase/aspartate Alanine aminotransferase (ALT/AST) increased aminotransferase/aspartate aminotransferase (ALT/AST) increased Skin and subcutaneous tissue disorders Very common: Rasha, pruritus Alopecia, rasha Common: Alopecia Pruritus Uncommon: Stevens-Johnson syndrome/toxic Stevens-Johnson syndromeb epidermal necrolysis Not known: Drug reaction with eosinophilia and systemic symptoms (DRESS) Musculoskeletal and connective tissue disorders Very common: Arthralgia, myalgia Bone pain, arthralgia, myalgia, back pain Common: Back pain General disorders and administration site conditions Very common: Fatigue, pyrexia, infusion-related Fatigue, pyrexia reactionsa Common: Chills Infusion-related reactionsa, chills Not known: Infusion site extravasationc Investigations Very common: Weight decreased Weight decreased a. Represents pooling of preferred terms.

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