Wirkstoffe & Arzneimittelsicherheit

Nebenwirkungen · Docetaxel Accord

Docetaxel Accord 20 mg/1 ml concentrate for solution for infusion Docetaxel Accord 80 mg/4 ml concentrate for solution for infusion Docetaxel Accord 160 mg/8 ml concentrate for solution for infusion · Abschnitt 4.8 · PDF-Seite 16

HOS-126748 · Präparat HOS-096309

MedDRA system Very common adverse Common adverse Uncommon adverse organ classes reactions reactions reactions Infections and Infection (G3/4: 7.8%) infestations Blood and lymphatic Neutropenia (G4: system disorders 91.7%); Anaemia (G3/4: 9.4%); Febrile neutropenia; Thrombocytopenia (G4: 0.8%) Immune system Hypersensitivity (G3/4: disorders 1.2%) Metabolism and Anorexia nutrition disorders Nervous system Peripheral sensory Peripheral motor disorders neuropathy (G3: 0.4%) neuropathy (G3/4: 0.4%) Cardiac disorders Cardiac failure; Arrhythmia (no severe) Vascular disorders Hypotension Gastrointestinal Nausea (G3/4: 5%); disorders Stomatitis (G3/4: 7.8%); Diarrhoea (G3/4: 6.2%); Vomiting (G3/4: 5%); Constipation Skin and subcutaneous Alopecia; tissue disorders Nail disorders (severe: 0.4%); Skin reaction (no severe) Musculoskeletal and Myalgia connective tissue disorders General disorders and Asthenia (severe: Infusion site reaction administration site 8.1%); conditions Fluid retention (severe: 1.2%); Pain Investigations G3/4 Blood bilirubin G3/4 AST increased increased (< 2.5%); (< 1%); G3/4 Blood alkaline G3/4 ALT increased phosphatase increased (< 1%) (< 2.5%)

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