Wechselwirkungen · Uptravi
Uptravi 100 microgram film-coated tablets Uptravi 200 microgram film-coated tablets Uptravi 400 microgram film-coated tablets Uptravi 600 microgram film-coated tablets Uptravi 800 microgram film-coated tablets Uptravi 1 000 microgram film-coated tablets Uptravi 1 200 microgram film-coated tablets Uptravi 1 400 microgram film-coated tablets Uptravi 1 600 microgram film-coated tablets · Abschnitt 4.5 · PDF-Seite 7–8
HOS-131261 · Präparat HOS-097037
7 Anticoagulants or inhibitors of platelet aggregation Selexipag is an inhibitor of platelet aggregation in vitro. In the phase 3 placebo-controlled study in patients with PAH, no increased risk of bleeding was detected with selexipag compared to placebo, including when selexipag was administered with anticoagulants (such as heparin, coumarin-type anticoagulants) or inhibitors of platelet aggregation. In a study in healthy subjects, selexipag (400 micrograms twice daily) did not alter the exposure to S-warfarin (CYP2C9 substrate) or R-warfarin (CYP3A4 substrate) after a single dose of 20 mg warfarin. Selexipag did not influence the pharmacodynamic effect of warfarin on the international normalised ratio.
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RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): placebo (HOS-088378) heparin (HOS-086930) warfarin (HOS-085950)
Vollständigen Kontext in der EMA-Fachinformation lesen →Quellennachweis
Version 2026-02-09T09:30:00Z · SHA-256 4d844da5fca00693ca71123bccf29f73c6fef6cc58001bcf22168f0e68d3056f · Passage 98918bb3292002b9f57f65e68f6e18631a0c4415cf44c12e3b1d30bec6a597bf · Zeichen 4468–5182 im Abschnitt