Wirkstoffe & Arzneimittelsicherheit

Nebenwirkungen · Keytruda

KEYTRUDA 25 mg/mL concentrate for solution for infusion · Abschnitt 4.8 · PDF-Seite 18–19

HOS-131806 · Präparat HOS-097138

18 MedDRA SOC Monotherapy In combination with In combination with and frequency chemotherapy, axitinib or lenvatinib category radiation therapy or chemoradiotherapy Rare Vogt-Koyanagi-Har Vogt-Koyanagi-Harad ada syndrome a syndrome Cardiac disorders Common cardiac arrhythmia‡ cardiac arrhythmia‡ cardiac arrhythmia‡ (including atrial (including atrial (including atrial fibrillation) fibrillation) fibrillation) Uncommon myocarditis¶, myocarditis⁎¶, myocarditis¶, pericarditis⁎, pericarditis⁎, pericardial pericardial effusion pericardial effusion effusion Vascular disorders Very common hypertension Common hypertension hypertension Uncommon vasculitis⁎ vasculitis⁎ Rare vasculitis⁎ Respiratory, thoracic and mediastinal disorders Very common dyspnoea, cough dyspnoea, cough dyspnoea, cough Common pneumonitis⁎ pneumonitis⁎ pneumonitis⁎ Gastrointestinal disorders Very common diarrhoea, diarrhoea, nausea, diarrhoea, abdominal abdominal pain⁎, vomiting, abdominal pain⁎, nausea, nausea, vomiting, pain⁎, constipation vomiting, constipation constipation Common colitis⁎, dry mouth colitis⁎, gastritis⁎, dry colitis⁎, pancreatitis⁎, mouth gastritis⁎, dry mouth Uncommon pancreatitis⁎, pancreatitis⁎, gastrointestinal gastritis , ⁎ gastrointestinal ulceration⁎ gastrointestinal ulceration⁎ ulceration ⁎

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