Nebenwirkungen · Opdivo
OPDIVO 10 mg/mL concentrate for solution for infusion. · Abschnitt 4.8 · PDF-Seite 39
HOS-133391 · Präparat HOS-097426
In patients treated with nivolumab in combination with ipilimumab (with or without chemotherapy), the incidence of nephritis or renal dysfunction was 5.4% (141/2626). Grade 2, Grade 3, and Grade 4 cases were reported in 2.0% (52/2626), 0.8% (21/2626), and 0.4% (11/2626) of patients, respectively. Two patients (< 0.1%) had a fatal outcome. Median time to onset was 2.6 months (range: 0.0-34.8). Resolution occurred in 110 patients (78.0%) with a median time to resolution of 5.9 weeks (range: 0.1-172.1+).
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Version 2026-08-19T11:11:00Z · SHA-256 1ce21ede7b3b9a8abc396626f301d2db3510ede7261a38fc34a275e7a180f454 · Passage 7a68e28b6d54f6cb842afb16a94f23f76cabf3611366b4d8761fbaf91b24a4ff · Zeichen 52431–52937 im Abschnitt