Wirkstoffe & Arzneimittelsicherheit

Wechselwirkungen · Genvoya

Genvoya 150 mg/150 mg/200 mg/10 mg film-coated tablets Genvoya 90 mg/90 mg/120 mg/6 mg film-coated tablets · Abschnitt 4.5 · PDF-Seite 18

HOS-134017 · Präparat HOS-097520

Genvoya is not expected to have a clinically relevant effect on plasma concentrations of the active metabolite of prasugrel. INHALED BETA AGONIST Salmeterol Interaction not studied with any of Concurrent administration of the components of Genvoya. salmeterol and Genvoya is not recommended. Co-administration with Genvoya may result in increased plasma concentrations of salmeterol, which is associated with the potential for serious or life-threatening adverse reactions. HMG CO-A REDUCTASE INHIBITORS Rosuvastatin (10 mg single dose)/ Elvitegravir: Concentrations of rosuvastatin are Elvitegravir (150 mg once daily)/ AUC: ↔ transiently increased when Cobicistat (150 mg once daily) Cmin: ↔ administered with elvitegravir and Cmax: ↔ cobicistat. Dose modifications are not necessary when rosuvastatin is Rosuvastatin: administered in combination with AUC: ↑ 38% Genvoya. Cmin: N/A Cmax: ↑ 89% Atorvastatin (10 mg single Atorvastatin: Concentrations of atorvastatin are dose)/Elvitegravir (150 mg once AUC: ↑ 160% increased when co-administered daily)/Cobicistat (150 mg once Cmin: N/A with elvitegravir and cobicistat. daily)/Emtricitabine (200 mg once Cmax: ↑ 132% Start with the lowest possible dose daily)/Tenofovir alafenamide of atorvastatin with careful (10 mg once daily) Elvitegravir: monitoring upon co-administration AUC: ↔ with Genvoya. Cmin: ↔ Cmax: ↔ Pitavastatin Interaction not studied with any of Caution should be exercised when the components of Genvoya. co-administering Genvoya with pitavastatin. Concentrations of pitavastatin may be increased when administered with elvitegravir and cobicistat.

Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.

RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): atorvastatin (HOS-086304) rosuvastatin (HOS-086307) salmeterol (HOS-086285) prasugrel (HOS-112066) pitavastatin (HOS-125743)