Wirkstoffe & Arzneimittelsicherheit

Wechselwirkungen · Genvoya

Genvoya 150 mg/150 mg/200 mg/10 mg film-coated tablets Genvoya 90 mg/90 mg/120 mg/6 mg film-coated tablets · Abschnitt 4.5 · PDF-Seite 19–20

HOS-134030 · Präparat HOS-097520

19  Medicinal product by Effects on medicinal product Recommendation concerning therapeutic areas levels. co-administration with Genvoya Mean percent change in AUC, Cmax, Cmin1 Tricyclic antidepressants (TCAs) Interaction not studied with any of Careful dose titration of the Trazodone the components of Genvoya. antidepressant and monitoring for Selective serotonin reuptake antidepressant response is inhibitors (SSRIs) Concentrations of antidepressant recommended. Escitalopram agents may be increased when co-administered with cobicistat. IMMUNOSUPPRESSANTS Ciclosporin Interaction not studied with any of Therapeutic monitoring is Sirolimus the components of Genvoya. recommended upon Tacrolimus co-administration with Genvoya. Concentrations of these immunosuppressant agents may be increased when administered with cobicistat. SEDATIVES/HYPNOTICS Buspirone Interaction not studied with any of Co-administration of Genvoya and Clorazepate the components of Genvoya. triazolam is contraindicated (see Diazepam section 4.3). With other Estazolam Triazolam is primarily metabolised sedatives/hypnotics, dose reduction Flurazepam by CYP3A. Co-administration may be necessary and concentration Lorazepam with Genvoya may result in monitoring is recommended. Triazolam increased plasma concentrations of Zolpidem this medicinal product, which is associated with the potential for serious or life-threatening adverse reactions.

Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.

RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): estazolam (HOS-086165) clorazepate (HOS-086164) lorazepam (HOS-085981) diazepam (HOS-085904) zolpidem (HOS-086327) serotonin (HOS-085477) trazodone (HOS-086251) tacrolimus (HOS-085202) buspirone (HOS-086325) sirolimus (HOS-085172) escitalopram (HOS-129417) triazolam (HOS-086168) flurazepam (HOS-086166)