Gegenanzeigen · Eptifibatide Accord
Eptifibatide Accord 0.75 mg/ml solution for infusion · Abschnitt 4.3 · PDF-Seite 3
HOS-135115 · Präparat HOS-097660
Eptifibatide Accord must not be used to treat patients with: - hypersensitivity to the active substance or to any of the excipients listed in section 6.1: - evidence of gastrointestinal bleeding, gross genitourinary bleeding or other active abnormal bleeding within the previous 30 days of treatment; - history of stroke within 30 days or any history of haemorrhagic stroke; - known history of intracranial disease (neoplasm, arteriovenous malformation, aneurysm); - major surgery or severe trauma within past 6 weeks; - a history of bleeding diathesis; - thrombocytopenia (< 100,000 cells/mm3); - prothrombin time > 1.2 times control, or International Normalized Ratio (INR) 2.0; - severe hypertension (systolic blood pressure > 200 mm Hg or diastolic blood pressure > 110 mm Hg on antihypertensive therapy); - severe renal impairment (creatinine clearance < 30 ml/min) or dependency on renal dialysis; - clinically significant hepatic impairment; - concomitant or planned administration of another parenteral glycoprotein (GP) IIb/IIIa inhibitor.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): creatinine (HOS-086273) prothrombin (HOS-085093)
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Version 2025-05-02T01:00:00Z · SHA-256 9396fc6df1ff96694d27eb7b74981a633ad8bf93b3393c54e43ba8b1ce931773 · Passage e61675eeabcf5692c1425aaf026323f7b0abf285e38940d3ca7a9cc8dcefbddd · Zeichen 0–1059 im Abschnitt