Nebenwirkungen · Onivyde pegylated liposomal (previously Onivyde)
ONIVYDE pegylated liposomal 4.3 mg/ml concentrate for dispersion for infusion · Abschnitt 4.8 · PDF-Seite 11–12
HOS-135465 · Präparat HOS-097714
11 Adverse reactions seen with ONIVYDE pegylated liposomal which led to its permanent discontinuation occurred in 9.5 % of patients; the most frequent adverse reaction resulting in discontinuation was neutropenia. Dose reductions of ONIVYDE pegylated liposomal due to adverse events (regardless of causality assessment), occurred in 52.4% of patients; the most frequent adverse events requiring dose reduction (≥5%) were diarrhoea, nausea, neutropenia and neutrophil count decreased. ONIVYDE pegylated liposomal was withheld due to adverse events (regardless of causality assessment), in 1.9% of patients; the most frequent adverse events requiring interruption were hypersensitivity and infusion related reactions that occurred in 0.5% of patients.
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Version 2024-11-29T09:48:00Z · SHA-256 6fe241cd32f9f9d3c8592da7ea124a85ef29388269021487b0409971bc580040 · Passage 57da8ce930be51d9473f3211f5ef0258ec74e1d2deb2542c4809718729776a8f · Zeichen 929–1679 im Abschnitt