Nebenwirkungen · Onivyde pegylated liposomal (previously Onivyde)
ONIVYDE pegylated liposomal 4.3 mg/ml concentrate for dispersion for infusion · Abschnitt 4.8 · PDF-Seite 16
HOS-135489 · Präparat HOS-097714
ONIVYDE pegylated liposomal in combination with oxaliplatin, 5-fluorouracil and leucovorin: In NAPOLI-3, safety data showed a higher incidence of diarrhoea reported in the NALIRIFOX arm for all grades and for grade 3 or 4. Grade 1 to 4 diarrhoea occurred in 64.3% of patients and Grade 3 or 4 diarrhoea occurred in 19.5% of patients receiving NALIRIFOX arm. Cholinergic reaction manifestations such as rhinitis, rhinorrhoea, salivary hypersecretion, flushing, hot flush and lacrimation increased, were reported in patients receiving NALIRIFOX.
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Version 2024-11-29T09:48:00Z · SHA-256 6fe241cd32f9f9d3c8592da7ea124a85ef29388269021487b0409971bc580040 · Passage d545a2b58f41363ec64e5db06b90efe61fd179275a08e23d6e3bb39ca55c933f · Zeichen 17742–18285 im Abschnitt