Nebenwirkungen · Erleada
Erleada 240 mg film-coated tablets · Abschnitt 4.8 · PDF-Seite 29–30
HOS-139442 · Präparat HOS-098330
In a randomised study (SPARTAN) of patients with nmCRPC, ischaemic heart disease occurred in 4% of patients treated with apalutamide and 3% of patients treated with placebo. In a randomised study 29 (TITAN) in patients with mHSPC, ischaemic heart disease occurred in 4% of patients treated with apalutamide and 2% of patients treated with placebo. Across the SPARTAN and TITAN studies, 6 patients (0.5%) treated with apalutamide and 2 patients (0.2%) treated with placebo died from ischaemic heart disease (see section 4.4).
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