Nebenwirkungen · Spravato
Spravato 28 mg nasal spray, solution · Abschnitt 4.8 · PDF-Seite 10
HOS-139766 · Präparat HOS-098400
Urinary tract symptoms Cases of interstitial cystitis have been reported with daily and long-term ketamine use at high doses. In clinical studies with esketamine, there were no cases of interstitial cystitis, however a higher rate of lower urinary tract symptoms was observed (pollakiuria, dysuria, micturition urgency, nocturia, and cystitis) in esketamine-treated patients compared with placebo-treated patients. In a long-term clinical trial with patients treated for a mean total duration of exposure of 42.9 months (up to 79 months), no cases of interstitial cystitis were observed.
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