Wechselwirkungen · Tadalafil Lilly
Tadalafil Lilly 10 mg film-coated tablets Tadalafil Lilly 20 mg film-coated tablets · Abschnitt 4.5 · PDF-Seite 35
HOS-140525 · Präparat HOS-098526
Anti-hypertensives (including calcium channel blockers) The co-administration of doxazosin (4 and 8 mg daily) and tadalafil (5 mg daily dose and 20 mg as a single dose) increases the blood pressure-lowering effect of this alpha-blocker in a significant manner. This effect lasts at least twelve hours and may be symptomatic, including syncope. Therefore this combination is not recommended (see section 4.4). In interaction studies performed in a limited number of healthy volunteers, these effects were not reported with alfuzosin or tamsulosin. However, caution should be exercised when using tadalafil in patients treated with any alpha-blockers, and notably in the elderly. Treatments should be initiated at minimal dose and progressively adjusted.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): alfuzosin (HOS-086139) doxazosin (HOS-088800) calcium (HOS-085615) tamsulosin (HOS-111257)
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Version 2026-01-28T13:35:00Z · SHA-256 591c030e92917080839aac0522f89e39ae339bcc4be9e68371f7969a185b0857 · Passage 63fce6f4951ba1724fde7395c01f90067319e48aa89105be2593a08d23ff9c30 · Zeichen 2987–3739 im Abschnitt