Nebenwirkungen · Rinvoq
RINVOQ 1 mg/ml oral solution · Abschnitt 4.8 · PDF-Seite 78
HOS-141751 · Präparat HOS-098682
In the placebo-controlled induction studies, the frequency of infection over 8 weeks in the upadacitinib 45 mg group compared to the placebo group was 20.7% and 17.5%, respectively. In the placebo-controlled maintenance study, the frequency of infection over 52 weeks in the upadacitinib 15 mg and 30 mg groups was 40.4% and 44.2%, respectively, compared to 38.8% in the placebo group. The long-term rate of infections for upadacitinib 15 mg and 30 mg was 64.5 and 77.8 events per 100 patient-years, respectively.
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