Wechselwirkungen · Zeposia
Zeposia 0.23 mg hard capsules Zeposia 0.46 mg hard capsules Zeposia 0.92 mg hard capsules · Abschnitt 4.5 · PDF-Seite 9
HOS-142255 · Präparat HOS-098792
In healthy subjects, a single dose of ozanimod 0.23 mg with steady state propranolol long acting 80 mg once daily or diltiazem 240 mg once daily did not result in any additional clinically meaningful changes in HR and PR interval compared to either propranolol or diltiazem alone. Caution should be applied when ozanimod is initiated in patients receiving treatment with a beta-blocker or a calcium- channel blocker (see section 4.4). Patients on other bradycardic medicinal products and on antiarrhythmic medicinal products (which have been associated with cases of torsades de pointes in patients with bradycardia) have not been studied with ozanimod.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): diltiazem (HOS-086288) propranolol (HOS-084529)
Vollständigen Kontext in der EMA-Fachinformation lesen →Quellennachweis
Version 2026-03-03T10:34:00Z · SHA-256 e1efa1853d4dbc887f7da13387736c7007c19f29d49a626a00d40b88c00a6a21 · Passage a87e77d94103f86a28f858a952f434343cf24af7628aa94d14921aeacb453cf8 · Zeichen 1675–2328 im Abschnitt