Wirkstoffe & Arzneimittelsicherheit

Nebenwirkungen · Enhertu

Enhertu 100 mg powder for concentrate for solution for infusion · Abschnitt 4.8 · PDF-Seite 11–12

HOS-144519 · Präparat HOS-099200

11 System organ class 5.4 mg/kg monotherapy 6.4 mg/kg monotherapy 5.4 mg/kg + Frequency category Adverse reaction Adverse reaction pertuzumab Adverse reaction Nervous system disorders Very common headachei headachei, dizziness, dysgeusia Common dizziness, dysgeusia dizziness, headachei, dysgeusia Eye disorders Very common dry eye Common dry eye, vision blurredj dry eye, vision blurredj vision blurredj Respiratory, thoracic and mediastinal disorders Very common interstitial lung diseasek, interstitial lung diseasek, interstitial lung cough cough diseasek, cough Common dyspnoea, epistaxis dyspnoea, epistaxis dyspnoea, epistaxis Gastrointestinal disorders Very common vomiting, nausea, nausea, vomiting, diarrhoea, diarrhoea, abdominal diarrhoea, constipation, vomiting, nausea, painl, constipation, abdominal painl, stomatitism, stomatitism, dyspepsia stomatitism abdominal painl, constipation, dyspepsia Common gastritis, abdominal dyspepsia, abdominal gastritis, distension, flatulence distension, gastritis, abdominal flatulence distension, flatulence Hepatobiliary disorders Very common transaminases increasedn transaminases increasedn transaminases increasedn Skin and subcutaneous tissue disorders Very common alopecia alopecia rasho, pruritus, alopecia Common rasho, skin rasho, pruritus, skin dry skin, skin hyperpigmentationp, hyperpigmentationp hyperpigmentationp pruritus Musculoskeletal and connective tissue disorders Very common musculoskeletal painq musculoskeletal painq musculoskeletal painq General disorders and administration site condition Very common fatiguer, pyrexia fatiguer, pyrexia, oedema fatiguer, pyrexia peripheral Common oedema peripheral mucosal inflammation

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