Nebenwirkungen · Fingolimod Accord
Fingolimod Accord 0.5 mg hard capsules · Abschnitt 4.8 · PDF-Seite 17
HOS-145277 · Präparat HOS-099320
Respiratory system Minor dose-dependent reductions in values for forced expiratory volume (FEV1) and diffusion capacity for carbon monoxide (DLCO) were observed with fingolimod treatment starting at month 1 and remaining stable thereafter. At month 24, the reduction from baseline values in percentage of predicted FEV1 was 2.7% for fingolimod 0.5 mg and 1.2% for placebo, a difference that resolved after treatment discontinuation. For DLCO the reductions at month 24 were 3.3% for fingolimod 0.5 mg and 2.7% for placebo (see also section 4.4, Respiratory effects).
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Version 2026-10-13T11:08:00Z · SHA-256 c38e617848fd32f3926aeca45feca8cfb462deb5bf6268c0fe28796f89fbcbff · Passage a97646922b22855002f371eb7289a0e6dd54981ed7f5a81ceeffcb563a5dadfa · Zeichen 11769–12335 im Abschnitt