Wechselwirkungen · Emcitate
Emcitate 350 microgram dispersible tablets · Abschnitt 4.5 · PDF-Seite 7
HOS-145401 · Präparat HOS-099344
Based on in vitro data there is an indication that tiratricol may induce CYP3A4 at a gut level and therefore medicinal products with narrow therapeutic indices that are dependent on CYP3A4, including but not limited to: alfentanil, cisapride, cyclosporine, ergot derivatives, fentanyl, pimozide, quinidine, sirolimus, tacrolimus, atorvastatin, lovastatin, and simvastatin should be used with caution. Similar precautions should be applied to other agents that are known to depend on CYP3A4 for metabolism. Medicinal products that are substrates of P-glycoprotein (P-gp) or Breast Cancer Resistance Protein (BCRP) efflux transporters with narrow therapeutic indices should also be used with caution.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): alfentanil (HOS-109375) cisapride (HOS-085610) lovastatin (HOS-086157) atorvastatin (HOS-086304) simvastatin (HOS-086158) quinidine (HOS-085593) tacrolimus (HOS-085202) pimozide (HOS-085600) sirolimus (HOS-085172) fentanyl (HOS-086196) cyclosporine (HOS-084512)
Vollständigen Kontext in der EMA-Fachinformation lesen →Quellennachweis
Version 2025-03-11T10:55:11Z · SHA-256 f1406017bf71ca6ed21c19c56ad9b2f42db03a6c0c95a8b1a995b810587719f2 · Passage 6b71938154e9c26e6761ac6836b035f6be162567267d17bd04a6aaa66f4eea80 · Zeichen 3537–4235 im Abschnitt