Wirkstoffe & Arzneimittelsicherheit

Nebenwirkungen · Rayvow

RAYVOW 50 mg film-coated tablets RAYVOW 100 mg film-coated tablets RAYVOW 200 mg film-coated tablets · Abschnitt 4.8 · PDF-Seite 7

HOS-146406 · Präparat HOS-099510

Blood pressure increase Single dose administration of lasmiditan may lead to a transient increase in blood pressure. In non-elderly healthy volunteers a mean increase from baseline in ambulatory systolic and diastolic blood pressure of approximately 2 to 3 mm Hg one hour after administration of 200 mg lasmiditan was observed, compared to an increase of about 1 mm Hg for placebo. In healthy volunteers over 65 years of age, the mean increase from baseline in ambulatory systolic blood pressure was 7 mm Hg one hour after administration of 200 mg lasmiditan compared to a mean increase of 4 mm Hg for placebo. By 2 hours, there were no increases in mean blood pressure with lasmiditan compared to placebo. Clinical data for the use of lasmiditan in patients with ischemic heart disease is limited.

Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.