Wirkstoffe & Arzneimittelsicherheit

Nebenwirkungen · Apixaban Accord

Apixaban Accord 2.5 mg film-coated tablets · Abschnitt 4.8 · PDF-Seite 14–15

HOS-146660 · Präparat HOS-099542

14 System organ class Prevention of Prevention of Treatment of Treatment of VTE in adult stroke and DVT and PE, VTE and patients who systemic and prevention prevention of have embolism in of recurrent recurrent undergone adult patients DVT and PE VTE in elective hip or with NVAF, (VTEt) in adult paediatric knee with one or patients patients from replacement more risk 28 days to surgery factors less than (VTEp) (NVAF) 18 years of age Haematochezia Uncommon Uncommon Uncommon Common Rectal haemorrhage, gingival Rare Common Common Common bleeding Retroperitoneal haemorrhage Not known Rare Not known Not known Hepatobiliary disorders Liver function test abnormal, Uncommon Uncommon Uncommon Common aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased Gamma-glutamyltransferase Uncommon Common Common Not known increased Alanine aminotransferase Uncommon Uncommon Common Common increased Skin and subcutaneous tissue disorders Skin rash Not known Uncommon Common Common Alopecia Rare Uncommon Uncommon Common Erythema multiforme Not known Very rare Not known Not known Cutaneous vasculitis Not known Not known Not known Not known Musculoskeletal and connective tissue disorders Muscle haemorrhage Rare Rare Uncommon Not known Renal and urinary disorders Haematuria Uncommon Common Common Common Anticoagulant-related Not known Not known Not known Not known nephropathy Reproductive system and breast disorders Abnormal vaginal haemorrhage, Uncommon Uncommon Common Very urogenital haemorrhage common§ General disorders and administration site conditions Application site bleeding Not known Uncommon Uncommon Not known Investigations Occult blood positive Not known Uncommon Uncommon Not known Injury, poisoning and procedural complications Contusion Common Common Common Common

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