Nebenwirkungen · Columvi
Columvi 2.5 mg concentrate for solution for infusion Columvi 10 mg concentrate for solution for infusion · Abschnitt 4.8 · PDF-Seite 20
HOS-149226 · Präparat HOS-100012
CRS of any grade occurred in 34.9% of patients following the first 2.5 mg dose of Columvi at Cycle 1 Day 8 with median time to onset (from start of infusion) of 12.6 hours (range: 4.4 to 54.7 hours) and median duration of 19.8 hours (range: 2.0 to 168.0 hours); in 14.4% of patients following the 10 mg dose at Cycle 1 Day 15 with median time to onset of 22.8 hours (range: 7.4 to 81.2 hours) and median duration of 10.6 hours (range: 1.0 to 248.5 hours); and in 9.3% of patients following the 30 mg dose at Cycle 2 with median time to onset of 23.5 hours (range: 14.7 to 33.4 hours) and median duration of
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Version 2026-10-20T13:00:00Z · SHA-256 2c5f4e2a70d7830059221b97eb832e6bb8ef846ec2df0243e5154b9f1ae1a38f · Passage 9938d24ed184c8d49d462a42ca4d214c258c6734cde350e63719344e9cf19b67 · Zeichen 20070–20676 im Abschnitt