Nebenwirkungen · Krazati
KRAZATI 200 mg film-coated tablets · Abschnitt 4.8 · PDF-Seite 9
HOS-150737 · Präparat HOS-100372
Increased blood creatinine Increased blood creatinine of any grade was reported 31.7% of patients, with < 1% of patients with grade ≥ 3 events. Median time to the first onset from first dose was 22 days, with a median duration of 19 days. Most cases were laboratory findings that did require intervention, and it remains unknown if these increases reflect a decrease in glomerular filtration rate. Blood creatinine may have also resulted from gastrointestinal fluid losses that may also be associated with dehydration and/or hyponatraemia.
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Vollständigen Kontext in der EMA-Fachinformation lesen →Quellennachweis
Version 2026-08-21T10:08:00Z · SHA-256 7b80e4bc7f6f1531858ad427e6ad8622b4c29caf51f3d5c29749df0a28c1f63b · Passage a91829dbc289994a8d44b0c14c4270447a21b00e053ce9517997b1633260f904 · Zeichen 8211–8750 im Abschnitt