Wechselwirkungen · Sugammadex Adroiq
Sugammadex Adroiq 100 mg/mL solution for injection · Abschnitt 4.5 · PDF-Seite 7
HOS-150951 · Präparat HOS-100426
The interaction between 4 mg/kg sugammadex and a progestogen was predicted to lead to a decrease in progestogen exposure (34% of Area Under the Curve (AUC) similar to the decrease seen when a daily dose of an oral contraceptive is taken 12 hours too late, which might lead to a reduction in effectiveness. For oestrogens, the effect is expected to be lower. Therefore, the administration of a bolus dose of sugammadex is considered to be equivalent to one missed daily dose of oral contraceptive steroids (either combined or progestogen only). If sugammadex is administered at the same day as an oral contraceptive is taken reference is made to missed dose advice in the package leaflet of the oral contraceptive. In the case of non-oral hormonal contraceptives, the patient must use an additional non hormonal contraceptive method for the next 7 days and refer to the advice in the package leaflet of the product.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): lead (HOS-085592)
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Version 2026-01-16T17:21:00Z · SHA-256 e7be1eb58d32faccb389767c0e9e5884057016dec53c72705ce1121f897cfb97 · Passage 8136a9bc95029d086e06faa44e0bf70b3374ad48b7e6d21d227d9825d45233c4 · Zeichen 3051–3965 im Abschnitt