Nebenwirkungen · Ruxolitinib Viatris
Ruxolitinib Viatris 5 mg tablets Ruxolitinib Viatris 10 mg tablets Ruxolitinib Viatris 15 mg tablets Ruxolitinib Viatris 20 mg tablets · Abschnitt 4.8 · PDF-Seite 21
HOS-153802 · Präparat HOS-101048
In the comparative period of the phase 3 acute GvHD study (REACH2), new or worsened lipase values were reported in 19.7% of patients in the ruxolitinib arm compared to 12.5% in the BAT arm; corresponding grade 3 (3.1% vs 5.1%) and grade 4 (0% vs 0.8%) increases were similar. During extended follow-up of patients treated with ruxolitinib, increased lipase values were reported in 32.2% of patients; grade 3 and 4 were reported in 8.7% and 2.2% of patients respectively. Elevated lipase was reported in 20.4% of paediatric patients (grade 3 and 4: 8.5% and 4.1%, respectively).
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