Nebenwirkungen · Tyverb
Tyverb 250 mg film-coated tablets · Abschnitt 4.8 · PDF-Seite 11
HOS-208955 · Präparat HOS-154213
Diarrhoea occurred in approximately 65 % of patients who received lapatinib in combination with capecitabine, in 64 % of patients who received lapatinib in combination with letrozole and in 62 % of patients who received lapatinib in combination with trastuzumab. Most cases of diarrhoea were grade 1 or 2 and did not result in discontinuation of treatment with lapatinib. Diarrhoea responds well to proactive management (see section 4.4). However, a few cases of acute renal failure have been reported secondary to severe dehydration due to diarrhoea.
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Version 2026-01-06T15:40:00Z · SHA-256 cc5bd96641c0b3f4003ec76839196782d898a5b2fc432b1735c84b65f7171b92 · Passage 22e31e955b073e430ca3a5604c54398000aa6000995377499fbcd1faf0adfcb9 · Zeichen 5994–6545 im Abschnitt