Wechselwirkungen · Olanzapine Teva
Olanzapine Teva 5 mg orodispersible tablets Olanzapine Teva 10 mg orodispersible tablets Olanzapine Teva 15 mg orodispersible tablets Olanzapine Teva 20 mg orodispersible tablets · Abschnitt 4.5 · PDF-Seite 25
HOS-209092 · Präparat HOS-154237
Inhibition of CYP1A2 Fluvoxamine, a specific CYP1A2 inhibitor, has been shown to significantly inhibit the metabolism of olanzapine. The mean increase in olanzapine Cmax following fluvoxamine was 54% in female non-smokers and 77% in male smokers. The mean increase in olanzapine AUC was 52% and 108% respectively. A lower starting dose of olanzapine should be considered in patients who are using fluvoxamine or any other CYP1A2 inhibitors, such as ciprofloxacin. A decrease in the dose of olanzapine should be considered if treatment with an inhibitor of CYP1A2 is initiated.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): ciprofloxacin (HOS-085177) fluvoxamine (HOS-085908)
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Version 2025-05-12T13:49:00Z · SHA-256 4c6933e864732db54f617a6615c3605a1299041a617de136aab779c18c8dbbe1 · Passage 07c0de7da7a5339a1a2c0a82e90f225c40b7e2880ccc5d906b0f4b4a62a88957 · Zeichen 658–1234 im Abschnitt