Wechselwirkungen · Clopidogrel Krka
Clopidogrel Krka 75 mg film-coated tablets · Abschnitt 4.5 · PDF-Seite 7
HOS-210636 · Präparat HOS-154555
Less pronounced reductions of metabolite exposure has been observed with pantoprazole or lansoprazole. The plasma concentrations of the active metabolite was 20% reduced (loading dose) and 14% reduced (maintenance dose) during concomitant treatment with pantoprazole 80 mg once daily. This was associated with a reduction of the mean inhibition of platelet aggregation by 15% and 11%, respectively. These results indicate that clopidogrel can be administered with pantoprazole.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): lansoprazole (HOS-085166) pantoprazole (HOS-085167) clopidogrel (HOS-087927)
Vollständigen Kontext in der EMA-Fachinformation lesen →Quellennachweis
Version 2025-05-14T09:49:00Z · SHA-256 de285f540dd9461c605738f58c4125215a83fbcefb35a3be3d9119eb1b2b68a9 · Passage 8741959ca26ef1991d9f10cb8dc0408f0677a8d230580e185084c52e76eb6108 · Zeichen 5175–5652 im Abschnitt