Nebenwirkungen · Clopidogrel Krka
Clopidogrel Krka 75 mg film-coated tablets · Abschnitt 4.8 · PDF-Seite 9
HOS-210653 · Präparat HOS-154555
In ACTIVE-A, the rate of major bleeding was greater in the clopidogrel + ASA group than in the placebo + ASA group (6.7% versus 4.3%). Major bleeding was mostly of extracranial origin in both groups (5.3% in the clopidogrel + ASA group; 3.5% in the placebo +ASA group), mainly from the gastrointestinal tract (3.5% vs. 1.8%). There was an excess of intracranial bleeding in the clopidogrel + ASA treatment group compared to the placebo + ASA group (1.4% versus 0.8%, respectively). There was no statistically significant difference in the rates of fatal bleeding (1.1% in the clopidogrel + ASA group and 0.7% in the placebo +ASA group) and hemorrhagic stroke (0.8% and 0.6%, respectively) between groups.
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Version 2025-05-14T09:49:00Z · SHA-256 de285f540dd9461c605738f58c4125215a83fbcefb35a3be3d9119eb1b2b68a9 · Passage d5f6d73af241915d518c994e8bafc451afde0a2f07e0a55990003553001353ac · Zeichen 1676–2380 im Abschnitt