Wirkstoffe & Arzneimittelsicherheit

Nebenwirkungen · Temozolomide Accord

Temozolomide Accord 5 mg hard capsules. Temozolomide Accord 20 mg hard capsules. Temozolomide Accord 100 mg hard capsules. Temozolomide Accord 140 mg hard capsules. Temozolomide Accord 180 mg hard capsules. Temozolomide Accord 250 mg hard capsules. · Abschnitt 4.8 · PDF-Seite 10–11

HOS-212030 · Präparat HOS-154808

10  Uncommon: Toxic epidermal necrolysis, Stevens-Johnson syndrome, angioedema, erythema multiforme, erythroderma, skin exfoliation, photosensitivity reaction, urticaria, exanthema, dermatitis, sweating increased, pigmentation abnormal Not known: Drug reaction with eosinophilia and systemic symptoms (DRESS) Musculoskeletal and connective tissue disorders Common: Myopathy, muscle weakness, arthralgia, back pain, musculoskeletal pain, myalgia Renal and urinary disorders Common: Micturition frequency, urinary incontinence Uncommon: Dysuria Reproductive system and breast disorders Uncommon: Vaginal haemorrhage, menorrhagia, amenorrhoea, vaginitis, breast pain, impotence General disorders and administration site conditions Very common: Fatigue Common: Fever, influenza-like symptoms, asthenia, malaise, pain, oedema, oedema peripherali Uncommon: Condition aggravated, rigors, face oedema, tongue discolouration, thirst, tooth disorder Investigations Common: Liver enzymes elevationj, weight decreased, weight increased Uncommon: Gamma-glutamyltransferase increased Injury, poisoning and procedural complications Common: Radiation injuryk a Includes pharyngitis, nasopharyngeal pharyngitis, pharyngitis Streptococcal b Includes gastroenteritis, gastroenteritis viral c Includes cushingoid, Cushing syndrome d Includes neuropathy, peripheral neuropathy, polyneuropathy, peripheral sensory neuropathy, peripheral motor neuropathy e Includes visual impairment, eye disorder f Includes deafness, deafness bilateral, deafness neurosensory, deafness unilateral g Includes earache, ear discomfort h Includes abdominal pain, abdominal pain lower, abdominal pain upper, abdominal discomfort i Includes oedema peripheral, peripheral swelling j Includes liver function test increased, alanine aminotransferase increased, aspartate aminotransferase increased, hepatic enzymes increased k Includes radiation injury, radiation skin injury † Including cases with fatal outcome

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