Wechselwirkungen · Myclausen
Myclausen 250 mg hard capsules · Abschnitt 4.5 · PDF-Seite 25
HOS-212966 · Präparat HOS-155006
Ciprofloxacin or amoxicillin plus clavulanic acid Reductions in pre-dose (trough) MPA concentrations of about 50% have been reported in renal transplant recipients in the days immediately following commencement of oral ciprofloxacin or amoxicillin plus clavulanic acid. This effect tended to diminish with continued antibiotic use and to cease within a few days of antibiotic discontinuation. The change in pre-dose level may not accurately represent changes in overall MPA exposure. Therefore, a change in the dose of Myclausen should not normally be necessary in the absence of clinical evidence of graft dysfunction. However, close clinical monitoring should be performed during the combination and shortly after antibiotic treatment.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): amoxicillin (HOS-085178) ciprofloxacin (HOS-085177) clavulanic acid (HOS-085179)
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Version 2026-04-10T14:45:00Z · SHA-256 5212e91cac7f54413fc4524ec82e254c35610b87ec825a71d5d295c67a8c8df9 · Passage ac3464cab49c7a55db61ca5503d08b75e40abbfb36bf9dfd2ba5e4e59e8680f1 · Zeichen 3087–3824 im Abschnitt