Nebenwirkungen · Komboglyze
Komboglyze 2.5 mg/850 mg film-coated tablets Komboglyze 2.5 mg/1,000 mg film-coated tablets · Abschnitt 4.8 · PDF-Seite 10
HOS-213510 · Präparat HOS-155120
The overall incidence of reported hypoglycaemia (recorded in daily patient diaries) was 17.1% in subjects treated with saxagliptin and 14.8% among patients treated with placebo. The percent of subjects with reported on-treatment events of major hypoglycaemia (defined as an event that required assistance of another person) was higher in the saxagliptin group than in the placebo group (2.1% and 1.6%, respectively). The increased risk of overall hypoglycaemia and major hypoglycaemia observed in the saxagliptin-treated group occurred primarily in subjects treated with SU at baseline and not in subjects on insulin or metformin monotherapy at baseline. The increased risk of overall and major hypoglycaemia was primarily observed in subjects with A1C < 7% at baseline.
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Version 2025-05-23T16:24:00Z · SHA-256 49284a2aa4bf5d4cc65df4fbea1683957d8ce0be034c6bcc4568504417c45a17 · Passage 9838ebe5453a6dbef9cb8d50df3aee48455aef803f155343c452962104982200 · Zeichen 5004–5774 im Abschnitt