Wechselwirkungen · Levetiracetam ratiopharm
Levetiracetam ratiopharm 100 mg/ml oral solution · Abschnitt 4.5 · PDF-Seite 27
HOS-213833 · Präparat HOS-155212
As in adults, there is no evidence of clinically significant medicinal product interactions in paediatric patients receiving up to 60 mg/kg/day levetiracetam. A retrospective assessment of pharmacokinetic interactions in children and adolescents with epilepsy (4 to 17 years) confirmed that adjunctive therapy with orally administered levetiracetam did not influence the steady-state serum concentrations of concomitantly administered carbamazepine and valproate. However, data suggested a 20 % higher levetiracetam clearance in children taking enzyme- inducing antiepileptic medicinal products. Dose adjustment is not required.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): valproate (HOS-085955) carbamazepine (HOS-085618)
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Version 2026-01-26T17:59:00Z · SHA-256 f83b9a6129b8ef5144ae86c3c40558f640cbeaa7f135ea04834f52af3d8864f5 · Passage 90bd7efd848411484c1d23dac6e7870b2ddf7271a19b71949784a4c684ce95c8 · Zeichen 413–1041 im Abschnitt