Nebenwirkungen · Giotrif
GIOTRIF 20 mg film-coated tablets GIOTRIF 30 mg film-coated tablets GIOTRIF 40 mg film-coated tablets GIOTRIF 50 mg film-coated tablets · Abschnitt 4.8 · PDF-Seite 10
HOS-214120 · Präparat HOS-155264
GIOTRIF Pemetrexed/ (40 mg/day) Cisplatin N = 229 N = 111 NCI-CTC Grade Any 3 4 Any 3 4 Grade Grade MedDRA Preferred Term % % % % % % Infections and infestations Paronychia1 57.6 11.4 0 0 0 0 Metabolism and nutrition disorders Decreased appetite 20.5 3.1 0 53.2 2.7 0 Respiratory, thoracic and mediastinal disorders Epistaxis 13.1 0 0 0.9 0.9 0 Gastrointestinal disorders Diarrhoea 95.2 14.4 0 15.3 0 0 Stomatitis2 69.9 8.3 0.4 13.5 0.9 0 Cheilitis 12.2 0 0 0.9 0 0 Skin and subcutaneous tissue disorders Rash3 70.3 14 0 6.3 0 0 Dermatitis acneiform4 34.9 2.6 0 0 0 0 Dry skin5 29.7 0.4 0 1.8 0 0 Pruritus6 19.2 0.4 0 0.9 0 0 Investigations Weight decreased 10.5 0 0 9.0 0 0 1 Includes Paronychia, Nail infection, Nail bed infection 2 Includes Stomatitis, Aphthous stomatitis, Mucosal inflammation, Mouth ulceration, Oral mucosa erosion, Mucosal erosion, Mucosal ulceration 3 Includes group of rash preferred terms 4 Includes Acne, Acne pustular, Dermatitis acneiform 5 Includes Dry skin, Skin chapped 6 Includes Pruritus, Pruritus generalised
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Version 2026-05-11T16:31:00Z · SHA-256 f9bce1a1b6cb4de0c103c283912dbcf5714eff2cc72ce93f25eb6c1e97fd88eb · Passage dfe5812861528deb9f476ada162adcf1cf3743746e46b34aa50e704eb2b906ee · Zeichen 5040–7353 im Abschnitt